kodolab Cell Membrane

Cell membrane transport: what gets through, and what it costs

A cell membrane is a phospholipid bilayer. Each lipid has a charged head that sits in water and two hydrocarbon tails that will not, so the sheet assembles itself with the tails hidden inside. The middle of every membrane is oil, and anything crossing has to get through it.

That decides the traffic. Small nonpolar molecules like oxygen and carbon dioxide dissolve into the oil and cross on their own, down their concentration gradient. Ions and polar molecules cannot, however small they are. Water crosses slowly both ways, and osmosis is the net of that headcount. Charged solutes get through only by proteins: a channel picks one ion and lets it run downhill, which is passive transport and costs nothing.

Moving a solute uphill costs ATP. The sodium-potassium pump spends one ATP to push three sodium ions out and pull two potassium ions in, against both gradients. That is active transport, and it is why a resting cell is negative inside. The gradients the pump builds are what channels, nerve impulses and secondary transport then spend.

In this lesson

  1. The bilayer
  2. What gets through
  3. Osmosis
  4. A channel
  5. The pump
  6. A cell at rest
one phospholipid One cis double bond, in the longer tail only. Bent chains cannot stack flush, so the membrane stays fluid.